Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
WTF.2: They Believe You Can Fly
也许同等重要的是，稳定或者下降的油价将会缓解通货膨胀压力使美国工人的工资更具有购买力。Renaissance Macro经济学家Neil Dutta 称“这对于国内需求来说是一个明确的积极的消息，人们将会有更多可以用来消费的钱”。
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Liu Fei was also a half-brother of the Emperor Wu of Han who ruled from 141BC to 97BC.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Few years in recent decades dawned with as much of a sense of pessimism as 2014. One consistent theme in the predictions for the year was that 2014 looked eerily similar to 1914. Most pundits predicted doom and gloom, especially in east Asia. Yet, while there were many horrific events — from thedowning of flight MH17 over Ukraine, to the abduction of hundreds of schoolgirls in Nigeria and the rise of the Islamic State of Iraq and the Levant — we have avoided outright world war. Now that the year is closed, with no repetition of 1914, it may be wise to investigate why the pundits were wrong, particularly on their ideas around the potential for conflict in Asia.
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
This journey into the mind and feelings of an 11-year-old-girl may be Pixar’s wildest adventure yet. It’s a very funny workplace sitcom (with exuberant, touching performances from Amy Poehler, Phyllis Smith, Mindy Kaling and others), an ingenious allegory of psychological development, and an almost unbearably moving and honest defense of the role of sadness in our lives. (Read the review.)
While the currency exchange limit has not changed, individuals are now required to disclose specific details on how they will use the funds. Funds can only be used towards current account spending such as tourism and shopping, overseas study, foreign medical care and consulting services. Real estate and other investment spending are explicitly forbidden.
Trends and targets in antiviral phototherapy
Mr. Sissako is both an indispensable political filmmaker and one of the great poets of contemporary cinema. His portrait of life under jihadi rule in northern Mali is brutal and shocking, but also gentle, generous and surprisingly funny. Mr. Sissako does not humanize violent extremists so much as demonstrate that they already belong to the species and reflect part of our common, tragic nature. But his movie also insists that the only effective and ethically serious way to oppose fanaticism is with humanism. Which is to say with irony, with decency and, perhaps above all, with art. (Read the review.)
It is also argued that Friends came about as the family unity of small-town America was being replicated in major urban centers as young people migrated without the maturity or streetsmarts to live alone. Before Friends, sitcoms tended to focus on family dynamics, with parents being the central characters. But when young people strike out on their own in the big city, who do they have for support? They must rely on each other to endure through the overwhelming confusion of youth.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
If the oldest man ever elected president can “tweet like a kindergartner,” why not flip the script and see if a youngster can be elected to office and govern wisely?
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
An earlier plan by activists and the US-based Human Rights Foundation to send 100,000 copies of the film in January was postponed until after last month's Lunar New Year.
Most technology developers are seeing app use grow and web use decline. That means companies have to have strong, fast, meaningful mobile platforms and those that don't lose customers.
ACE2 as a potential therapeutic target for pandemic COVID-19
China does not want to see a trade war between the US and China. That would not make our trade fairer and cause loss for the both sides.
Diagnostic technologies for COVID-19: a review
Iron ore imports fell 12.3 per cent by volume in October from the previous month and 4.9 per cent from the same month a year earlier while coal imports were down 21.4 per cent from September and 30.7 per cent from a year earlier, according to Chinese customs data.
China had a full-year GDP target of “around 6.5 per cent” for 2017.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
However, you know when your cycles are over when the washer and dryer stop making noise. And you know when the weather is ugly by simply looking outside, or checking your weather app. Therefore, the product is basically just another way hackers can get into your home.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
“暂时没有名字的泡沫”依然是泡沫。但美国人太不在乎、太麻木、太不接受事实，所以听不到警告声音。这让我想起2000年3月20日我一篇文章的标题：“下次崩盘，对不起你们永远不会听到它的到来”(Next crash, sorry you'll never hear it coming)。
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
China’s commercial aerospace ambition has long been known, but a few recent milestones are bringing it closer to realization.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
Yunge from the Desert
Influenza neuraminidase: A druggable target for natural products
John Hummel, chief investment officer for AIS Group, a fund manager with $400 million under management, said all the new sources of global oil are expensive to extract, and he sees U.S. shale output falling by 2015.
No. The Bank of Japan’s life will get tougher in 2018 as the US Federal Reserve tightens policy and widens the interest rate gap with Japan. But governor Haruhiko Kuroda is determined to hike rates in response to one thing only: inflation. The BoJ may let the yield curve climb a little if prices start to accelerate, but real interest rates in Japan will end 2018 no higher than at the start of the year.
The former Miss Israel, Gal Gadot spot 6th in the list of 10 most beautiful women of 2015. She is the leading fashion model for the clothing company Castro. Gadot is known for her role as Gisele Yashar in The Fast and the Furious film series.
The University of Pittsburgh team used stem cells made from skin to make MCPs, a special kind of cell that acts as a precursor to cardiovascular tissue. They then placed these cells on a 3-D scaffold designed to support a mouse heart. Within 20 days, the new heart began beating at 40 to 50 beats per minute.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Miranda Lambert “Bathroom Sink” (RCA Nashville)
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
China’s commercial aerospace ambition has long been known, but a few recent milestones are bringing it closer to realization.
1997：H5N1传染人类1997: H5N1 Infects Humans
又或者，今年是一群有跟虐待、性或其他有关的故事要讲的女性。她们其中几个人在我们的页面上分享了“我也是”(#MeToo)的经历。卡洛塔·加尔(Carlotta Gall)讲述了汉达·阿亚里(Henda Ayari)的故事。后者是一名拥有北非血统的法国公民，也是一名反萨拉菲派活动人士。她指控牛津大学某知名教授强奸了她。
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
但1998年的记录现已被每四、五年一次的新记录多次打破，而2014年的记录是在没有显著厄尔尼诺现象发生的年度创下的。加文·A·施密特(Gavin A. Schmidt)是位于曼哈顿的美国宇航局戈达德太空研究所的所长，他说，下一次的强厄尔尼诺现象可能会打破所有的温度记录。
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
8. Jessica Gomes
Inhibition of SARS coronavirus helicase by bismuth complexes
圣加伦大学校友的薪资排名第三，为114449美元（按购买力平价调整后），排在艾哈迈达巴德的印度管理学院(Indian Institute of Management)和印度管理学院班加罗尔分校(IIM Bangalore)之后，这两所商学院校友的平均薪资分别为116476美元和116094美元。圣加伦大学还在职业服务质量方面排名第一。
The second-best song that Shirley Bassey performed for the James Bond franchise is still one of the best. For a series that, on some level, has always been about wish fulfillment, listening to one of the great singers belt powerful notes about avarice seems just about right. So say what you will about the film (it's not on many of the lists of James Bond's best), but Bassey had good material here and she knocked it out of the park.
In news that should come as little surprise to global air travelers, Singapore's done it again.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
To put this all in a bit more perspective, the current World Cup is averaging more goals than any of the top leagues around the world averaged in 2013/14. TheNetherlands' Eredivisie was the highest scoring of the top European leagues at 3.20 and the Bundesliga was just a shade behind at 3.16. No other top European league averaged more than 2.80 last season. In theAmericas, Major League Soccer is the current pace setter at 2.89 goals per game.
The thing about the Mavericks is that this is not at all how Dirk should go out. That team has been so solid his entire career. To have a busted season now is painful. Maybe he ought to have joined Kobe, KG, and Big Fundamental last summer.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
But I don't think you can say that to us anymore. Are we even on your list of priorities? My father always says "You are what you do, not what you say." 但我不能再相信这样的话了，孩子们还是你们的优选名单吗？我爸爸总是说：“听其言，观其行，是认识一个人最好的方法”。
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
I expect more companies to develop leaders who know how to manage networks — not just the traditional internal network of employees, but more loosely connected webs of suppliers and contractors, managed remotely via the internet and social media.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Look up "side-splitting humor" in the dictionary and you should probably come across the trailer for Girls Trip, which is the funniest movie of 2017, no contest.
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
James Bond Themes Honorable Mention: "Surrender" by K.D. Lang
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Putin had positive things to say about the Russian economy, saying it has "passed the crisis -- at least, the peak of the crisis."
Paris is in third place with 18.03 million forecast visitors.
He then pressed all the buttons in the hope to get the elevator to work again, but to no avail. Sun then punched the "stop" button, to lock the elevator and secure it won't move.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
4.Virtual Assistant: 17.6 percent increase
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
The truth is, to shut our door to the outside world would not help China do its own things well, so China will continue to open to the outside world, with this opening-up being a gradual process.
由于州政府和市政府试图打击不法的旅馆经营者，明年可能会出台一项规定。而与此同时，房产租赁网站Airbnb将游说政府改变法规。“你会看到，规范这一市场的要求会变得更加迫切。”代表租户的律师塞缪尔·J·希莫尔斯泰因(Samuel J. Himmelstein)说。
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Others are Ouyeel, a unit of Shanghai Baosteel Group that provides financing for steel traders; and Small Entrepreneur, part of China Merchants Bank — the country’s sixth-largest lender — which focuses on wealth management.
While he wins the Nerb prize, the sister prize, for the best verb masquerading as a noun, is won by another consultant who referred to a “global touch-base”.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
There will no longer be any legal obstacle to the implementation of a universal two-child policy, if the draft amendment to the family planning law is approved by the top legislature by Sunday.
Contributing columnist Antoine Gelain is the managing director of Paragon European Partners. He is based in London.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
At the same time, she said, other countries have seen their tourist numbers spike as the currencies weaken.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
In fact, create a hard and fast rule to keep work and job searching separate. That means no sneaking out for a phone interview. No browsing job boards. No applying or networking with your work email address. "You don't watch porn at work, and you don't work on your résumé at work," Kay says. "You just don't."
It adds up to a pointed reminder that Her Royal Swiftness can reclaim her place at pop's cutting edge whenever she feels like it.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
37| “Anomalisa” (Charlie Kaufman/Duke Johnson)|
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Then in 2011, her mother Melissa was signed up to appeared as part of the Lifetime reality series Dance Moms.
A modular microarray imaging system for highly specific COVID-19 antibody testing
The S&P 500’s total return of 14% this year was 40% higher than its 25-year average annual gain. Wall Street’s chief strategists spent much of the last 12 months revising their targets higher from behind. The index printed over 50 all-time record closes, with nearly all investment management professionals racing to at least pull even. A few characteristics made the U.S. stock market particularly difficult to keep up with this year.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
A person walks through snow Tuesday in Belington, West Virginia. Superstorm Sandy buried parts of West Virginia under more than a foot of snow on Tuesday.
Kobe Bryant really hasn't changed that much since high school, even though it's been 16 years since he's walked the halls of Lower Merion High School.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
约瑟夫?斯蒂格利茨(Joseph Stiglitz)等诺贝尔经济学奖得主、比尔?麦吉本(Bill McKibben)等环保活动人士、乔治?索罗斯(George Soros)及新经济思维研究所(Institute for New Economic Thinking)、阿尔?戈尔(Al Gore)和其他现代思想家全都提醒我们，传统经济学家（以及他们效力的银行、企业和政府机构）都已对坏的经济学理论成瘾，他们在破坏美国的未来。
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
According to a research report on 2016 graduates released by 51job.com, a leading job hunting platform in China, 52.11% of college graduates found employment or started their own business.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
“The worker threw a brick through the window with the words ‘I quit’ written on it.”
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Will the AT&T/Time Warner merger go through without big remedies (such as the sale of CNN)
12. Scientists modify photosynthesis to boost crop yield
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
然而据北京出入境边防检查总站(Beijing General Station of Exit and Entry Frontier Inspection)称，只有14,000名旅客办理了过境免签手续，远低于官方此前预计的20,000人。
China Everbright, the financial conglomerate that bought the Dah Sing Financial Centre for HK$10bn ($1.29bn), is just one of a number of mainland Chinese companies to have splashed out on headquarters in the city over the past year.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
会。梅亚德是执政党革命制度党(PRI)的候选人。他主要的竞争对手是强硬的左翼领导人安德烈斯曼努埃尔洛佩斯奥夫拉多尔(Andrés Manuel López Obrador)——可以感召人群的激情演说家。梅亚德需要克服很多问题：在去年1月一夜间把油价上调20%、引发通胀飙升后，他必须说服选民自己仍然是可以信任的。他还必须证明自己是个有主见的人，而不仅仅是这届不受欢迎的政府的傀儡——在遏制猖獗的腐败和犯罪行为方面，这届政府极为失败。但是凭借强大的PRI拉票机器，他可能势不可挡。在墨西哥只有一轮选举的体制下，30%的选票可能就足以让他当选总统了。
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
法国兴业银行(Societe Generale)国际策略师基特?朱克斯(Kit Juckes)说，过去30年破灭的三个世界级金融大泡沫背后，都是“美联储(Fed)太久时间将政策利率维持在名义经济增长率之下”。
Anti-HIV drug repurposing against SARS-CoV-2
Length-scale dependence of protein hydration-shell density
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
More than 90 per cent of alumni from the most recent graduating classes accepted a job offer within three months of completing their programme.
About this collection
●"Pope Francis Shocks World, Endorses Donald Trump for President, Releases Statement"
China must walk a narrow line at a time when its outgoing leadership is reluctant to take any far-sighted decisions.